EPINASTINE HCL
Epinastine hydrochloride
CAS: 108929-04-0;80012-44-8
Molecular Formula: C16H16ClN3
EPINASTINE HCL - Names and Identifiers
| Name | Epinastine hydrochloride |
| Synonyms | Elestat Alesion WAL-801CL EPINASTIN HCL Epinastin Hcl EPINASTINE HCL Epinastine hcl Epinastine hydrochloride Epinastine Hydrochloride f)imidazo(1,5-a)azepin-3-amine,9,13b-dihydro-ih-dibenz(hydrochloride 9,13b-Dihydro-1H-Dibenz[c,f]imidazo[1,5-α]azepin-3-amine Hydrochloride 3-Amino-9,13b-Dihydro-1h-Dibenz[C,F]Imidazo[1,5-A]Azepine Hydrochloride 3-AMINO-9,13B-DIHYDRO-1H-DIBENZ[C,F]IMIDAZO[1,5-A]AZEPINE HYDROCHLORIDE |
| CAS | 108929-04-0 80012-44-8 |
| EINECS | 629-843-8 |
| InChI | InChI=1/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H |
| InChIKey | VKXSGUIOOQPGAF-UHFFFAOYSA-N |
EPINASTINE HCL - Physico-chemical Properties
| Molecular Formula | C16H16ClN3 |
| Molar Mass | 285.77 |
| Melting Point | 273-275°C |
| Boling Point | 428°C at 760 mmHg |
| Flash Point | 212.7°C |
| Solubility | H2O: soluble38mg/mL |
| Vapor Presure | 1.56E-07mmHg at 25°C |
| Appearance | solid |
| Color | white |
| Storage Condition | 2-8°C |
| MDL | MFCD00933434 |
| In vitro study | In the guinea pig ileum, receptor binding studies showed that Epinastine has a high affinity for H1-receptors. At low concentrations, Epinastine was able to displace specific [Epinastine inhibited the release of histamine from rat peritoneal mast cells elicited by the antigen-antibody reaction and Compound 48/80 in Locust neural tissue. Epinastine was similarly effective in inhibiting Compound 48/80-induced histamine release from isolated rat peritoneal mast cells, or rat septal membranes. Epinastin not only can effectively inhibit Ca Epinastine show time-and dose-dependent inhibitory effect on IL-8, IL-8 is one of the Eosinophil chemotactic factors released by eosinophils isolated from allergic diseases. |
| In vivo study | Epinastine inhibits histamine-induced skin or lung responses in rats, dogs, and guinea pigs. |
EPINASTINE HCL - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | HO4360000 |
| HS Code | 2933992600 |
| Toxicity | LD50 in male, female rats (mg/kg): 314, 192 orally; 17, 22 i.v. (Nishikawa) |
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Featured ProductsMultiple SpecificationsSpot supply
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Product Name: Epinastine hydrochloride Request for quotationCAS: 108929-04-0
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Mobile: 18916960931
QQ: 3623107365
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Product Name: Epinastine hydrochloride Visit Supplier Webpage Request for quotationCAS: 108929-04-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: WAL801 hydrochloride Visit Supplier Webpage Request for quotationCAS: 108929-04-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Multiple SpecificationsSpot supply
Product Name: Epinastine HCl Visit Supplier Webpage Request for quotationCAS: 80012-44-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 3-Amino-9,13b-Dihydro-1H-Dibenzo[c,f]Imidazo[1,5-a]Azepine Hydrochloride Visit Supplier Webpage Request for quotationCAS: 108929-04-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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